Dosing Guide

Dosing Guide

CBD

Dosing is dependent on our individual bodies and there is not an official serving size. It can take 2-3 weeks to determine the proper dosage, but once you witness CBD’s effects on your body you’ll be in a better position to decide how much to take and when to take it, so be patient and take your time. 

If you are taking CBD for stress and anxiety, it is suggested to take smaller doses twice a day, say morning and evening. If you are taking CBD for physical pain, you might want to take one or more larger doses. And for people who menstruate, it is often helpful to take CBD a day or two before your period starts, to reduce cramping and other period pain. Everyone’s body is different when it comes to CBD, and many people need to build up the substance in their system in order to start seeing benefits. If you don’t see results right away, keep up your daily doses for four weeks, paying close attention to the changes you sense in your body.  

As a baseline, a suggested dosage is 0.25mg CBD multiplied by your body weight in pounds on a daily basis.  Therefore, a 120 pound person should take 30mg CBD daily (0.25 x 120 = 30), and a 200 pound person should take 50mg CBD daily (0.25 x 200 = 50). 

With this guideline, a 120 pound person would take 15 mg twice a day, while a 200 pound person would take 25 mg twice a day. 

https://championsandlegends.com/blogs/education/dosage-tips

THC

If you’re new to cannabis edibles and don’t know your optimal THC dose, it’s best to start low and go slow. For a first time experience we recommend starting with 5 mg of THC and waiting up to 2 hours to monitor effects. Do not pull the classic move of thinking it’s not working and then taking more and getting way too high. Too much THC can result in paranoia and other undesirable feelings.

First Time: 5 Mg

Lite: 10 Mg

Moderate: 20 Mg

Strong: 35 Mg

Very Strong: 50+ Mg

Onset time: 30-60 minutes

Peak High: 2-4 hours

Duration: 5-7 hours

https://www.analyticalcannabis.com/articles/how-long-do-edibles-last-312084

https://www.periodicedibles.com/original-caramels/dose

Shrooms

Microdose: 0.1-0.25 gram. A microdose shouldn’t affect your day-to-day activities, such as work and socializing with others. You may experience some changes in mood, thinking, concentration, energy levels. Many people report feeling clear and happy. A microdose is usually a 10th to a 20th of a normal dose that would produce psychedelic effects. 

Low Dose: 0.25-1 gram. A low magic mushroom dosage is a dose where you can start to feel some psychedelic effects. There is no exact ‘point’ at which a microdose becomes a low dose, but there are some signs that distinguish the two. If you take a low mushroom dosage, you may experience slight changes in visual perception, such as colors appearing enhanced, a slight body high, a giddy feeling, or feeling a bit euphoric or anxious. Doses do vary between mushroom species, based on potency. However, a low dose of magic mushrooms is generally 

Moderate Dose: 1 to 2 grams. When you take a moderate dose of magic mushrooms, there will be more intense psychedelic effects, such as: more noticeable enhancement of colors; visual distortions, such as objects morphing or ‘breathing’; seeing geometric patterns, synesthesia or ‘crossing of the senses’ (e.g. ‘hearing colors’ or ‘seeing sounds’); increased appreciation of music; laughter; noticeable body high; changes to tactile sensations; introspection; euphoria; feelings of gratitude; confusion, paranoia, fear, or anxiety; time dilation (e.g. minutes feeling like hours). 

Strong Dose: 2-4 grams. When you take a high dose of magic mushrooms, you can expect intense effects, with major changes to your thoughts, cognition, perception, and mood. You may experience the effects of a moderate dose (at a greater intensity), as well as: visual and auditory hallucinations; visions – a kind of waking dream state; profound insights; a feeling of dissociation from your body; the feeling of a ‘divine presence’; and/or the possibility of ‘ego death’, where you lose your sense of self-identity. 

Very Strong Dose: 4+ grams. A very high dose of magic mushrooms provides a different kind of experience compared to the other mushroom dosages described. It’s at this dose that you can expect to have a mystical experience, which may include: a sense of interconnectedness or oneness (the feeling of being everything); strong likelihood of ego dissolution; the feeling of gaining hidden knowledge; communication with beings and entities; ineffability (being unable to accurately describe the experience); timelessness, existing for eternity or an eternal present; and/or the feeling of being in an infinite void. Very strong doses should only be taken with an experienced guide in a controlled environment, such as at a mushroom ceremony or retreat. 

Onset: 30-60 minutes

Peak: 3-4 hours after ingesting

Duration: 4-6 hours

https://blog.retreat.guru/mushroom-dosage

https://doubleblindmag.com/mushrooms/how-to-take-shrooms/how-long-to-kick-in/

LSD

Lysergic acid diethylamide-25, or LSD, is a semi-synthetic derivative of a group of compounds called lysergamides. These compounds are primarily found in a species of rye fungus called ergot. LSD works by activating serotonin receptors in the brain — which produces changes in visual, auditory, and tactile perception. It promotes introspection and dissolving of the “ego”. 

Microdose: Similar to shrooms, a microdose is about a 10th – 20th of a regular dose, so about 10-20 Mcg or μg. Micrograms (Mcg) and μg are the same. The purpose of microdosing isn’t to “trip.” It’s used as a tool to promote a heightened sense of focus and productivity, boost creativity, and support mental health conditions like depression and anxiety over long periods of time. The main benefits of microdosing appear gradually over the course of several weeks or months. 

Mild Dose: 25-75 Mcg. A threshold/mild experience.  A mild mood altering experience, with mild euphoria.  Visual hallucinations are limited to color sensations, mild “breathing” effects, and psychedelic color flashes, especially when viewing bright objects like computer monitors or phones.  Main trip may last four to six hours, but comedown may extend to standard length. 

Moderate Dose: 75-150 Mcg. A substantial experience.  All phases of the LSD experience described above are experienced.  At lower range, hallucinations are limited to a breathing effect, strong psychedelic colors, mild visual hallucinations (e.g., objects appear distorted).  At the higher end of range, full hallucinations, with objects appearing that do not exist, substantial distortion of actual objects, strong swaying of objects like trees, cartoon-like images.  Sense of self intact; standard logic still applying, but self-judgment and fear/anxiety greatly reduced.

Strong Dose: 150-300 Mcg. Beautiful colors are everywhere, with stronger visual hallucinations overall. Closed eye visuals are very apparent. Life changing, spiritual experiences or realization may occur. Anxiety may occur. The peak of this trip can be very intense or even scary but like any LSD trip, once the peak effects are over, a state of contentment may follow.  Sense of self remains intact, but irrational thoughts and obsessive thought patterns may arise, including “thought loops” or “looping”.  Panic about one’s own safety, of the safety of loved ones, may occur.  Closed-eye visuals are very strong at this dose. 

Very Strong Dose: 300-400 Mcg. Strong visuals, loss of sense of self/ego dissolution begins.  Standard logic may no longer apply at points.  Visuals are intense.  May be difficult to walk or understand normal day to day activities. Time distortions may become intense, including feelings of time stopping.  Sense of self often gone/full ego dissolution is possible.  Body movement becomes difficult and disorienting. No longer able to form  rational thoughts as one enters a temporary psychotic state (not generally unpleasant). Very intense visual hallucinations. Closed eye hallucinations may be overwhelming, with some wishing to be able to escape the intensity of the trip. 

Extreme Dose: 400+ Mcg. Total loss. Very strong and elaborate hallucinations. Objects appearing that do not exist. Strong loss of reality. Entire ego dissolution likely.  Strong religious or symbolic imagery may occur/mystical experiences reported. Often overwhelming, and we do not recommend taking this amount.

Onset: 20-90 minutes

Peak: 3-4 hours

Duration: 6-10 hours

https://www.globaldrugsurvey.com/gds-2018/thinking-of-using-lsd-for-the-first-time-heres-our-checklist-to-help-you-stay-safe

DMT

N,N-dimethyltryptamine, or DMT is a naturally-occurring alkaloid of the tryptamine family found throughout nature. Trace amounts of this molecule can be found in various plant and animal species. The human brain manufactures its own DMT in the pineal gland.

DMT is closely related to serotonin — one of the primary neurotransmitters in the human brain. Serotonin is responsible for regulating emotion, conscious thought, and much more. DMT is believed to play a similar role, and many experts believe it’s responsible for inducing dream states while we sleep.

Threshold Dose: 10-15 Mg. The minimum dose of a drug that will produce a detectable degree of any given effect. 

Light Dose: 15-25 Mg. Very mild psychoactive effects, with slight physical effects as well. Doses this size are best for those who want to only experience a gentle dosage of tryptamine instead of a full-fledged out-of-body experience. 

Regular Dose: 25-40 Mg. A more potent trip, though it may not be enough to trigger whole hallucinations. For beginners, this is a good starting dose. Trips are mild and only last around 10 or 15 minutes, but it will be different for everyone. 

High Dose: 40-50 Mg. The full effects of the DMT are said to be felt, including hallucinations and out-of-body experiences, and trips are full-bodied, potent, and transformative for so many. 

Very High Dose: 50+ Mg. Typically, any more than 50 mg. of DMT is considered extremely potent, even for the most experienced consumers. Do not consume this amount of DMT if you have never experienced the drug before, as this could result in adverse reactions and uncomfortable trips.

Onset: 1 minute

Peak: 10-20 minutes

Duration: 30-45 minutes

Dangerous Interactions:

Lithium: Lithium is commonly prescribed for the treatment of bipolar disorder. There is a large body of anecdotal evidence that suggests taking it with psychedelics significantly increases the risk of psychosis and seizures. As a result, this combination is strictly discouraged.

Cannabis: Cannabis may have an unexpectedly strong and unpredictable synergy with the effects of DMT. Caution is advised with this combination as it can significantly increase the risk of adverse psychological reactions like anxiety, paranoia, panic attacks, and psychosis. Users are advised to start off with only a fraction of their normal cannabis dose and take long breaks between hits to avoid unintentional overdose.

Stimulants: Stimulants like amphetamine, cocaine or methylphenidate affect many parts of the brain and alter dopaminergic function. This combination can increase the risk of anxiety, paranoia, panic attacks, and thought loops. This interaction may also result in an elevated risk of mania and psychosis.

Tramadol: Tramadol is well-documented to lower the seizure threshold and psychedelics may act to trigger seizures in susceptible individuals.

https://psychonautwiki.org/wiki/DMT

https://drugs.tripsit.me/dmt

2C-B-Fly

2C-B-FLY is a lesser-known novel psychedelic substance of the phenethylamine and benzodihydrodifuran classes that produces an array of psychedelic and entactogenic effects when administered. Reports have characterized its effects profile as possessing features of 2C-B, mescaline and MDA, with a duration of 6–8 hours, or longer at higher doses.

Cognitive Effects: 2C-B-FLY tends to maintain a level of relatively normal and sober thought structure regardless of the subjective visual, physical and cognitive accompanying effects intensity. This leaves the user in control in a manner which would not be possible on many compounds such as DMT or LSD due to their accompanying confusion and delusions.

Microdose: 1-2 Mg

Threshold Dose: 5 Mg. 

Light Dose: 10 Mg

Standard Dose: 25 Mg

Heavy Dose: 25+ Mg

Onset: 30-60 minutes

Peak: 2-4 hours

Duration: 6-8 hours

Dangerous Interactions:

Lithium is commonly prescribed for the treatment of bipolar disorder. There is a large body of anecdotal evidence that suggests taking it with psychedelics significantly increases the risk of psychosis and seizures. As a result, this combination is strictly discouraged.

Cannabis may have an unexpectedly strong and unpredictable synergy with the effects of DMT. Caution is advised with this combination as it can significantly increase the risk of adverse psychological reactions like anxiety, paranoia, panic attacks, and psychosis. Users are advised to start off with only a fraction of their normal cannabis dose and take long breaks between hits to avoid unintentional overdose.

Stimulants like amphetamine, cocaine or methylphenidate affect many parts of the brain and alter dopaminergic function. This combination can increase the risk of anxiety, paranoia, panic attacks, and thought loops. This interaction may also result in an elevated risk of mania and psychosis.

Tramadol is well-documented to lower the seizure threshold and psychedelics may act to trigger seizures in susceptible individuals.

https://psychonautwiki.org/wiki/2C-B-FLY

4-HO-MiPT

N-Methyl-N-isopropyltryptamine, or MiPT is a lesser-known psychedelic substance of the tryptamine class. It is structurally related to tryptamines like DMT, DiPT, and MET, although it is reported to produce qualitatively different effects. Its effects are generally described as mild, indistinct, and highly variable between users. MiPT is a tryptamine derivative and Psilocin analogue. It has been reported as having comparable effects to psychedelic mushrooms, though with a shorter duration.

The cognitive effects of MiPT are reported to be mild for a psychedelic. Rather than producing distinct perceptual distortions, it is reported instead to act as a mild sensory amplifier. Effects can include brightened colors, visual distortions, altered perception, a sense of connectedness with the world around you, heightened emotions, paranoia, unwanted thoughts.

Threshold Dose: 5-10 Mg

Light Dose: 10-15 Mg

Common Dose: 15-25 Mg

Strong Dose: 20-30 Mg

Very Strong Dose: 40+ Mg

Onset: 20-90 minutes

Peak: 2-3 hours

Duration: 4-6 hours

https://drugs.tripsit.me/4-ho-mipt

https://psychonautwiki.org/wiki/Mipt

Methallylescaline (MaL)

4-Methallyloxy-3,5-dimethoxyphenethylamine (also known as methallylescaline and MAL) is a synthetic psychedelic substance of the phenethylamine chemical class. It is reported to produce hallucinogenic and stimulant effects comparable to that of other mescaline analogs.

Stimulation: In terms of its effects on the physical energy levels of the user, methallylescaline is usually considered to be very energetic and stimulating. For example, when taken in any environment it will usually encourage physical activities such as running, walking, climbing or dancing. In comparison, other more commonly used psychedelics such as psilocin are generally sedating and relaxed.

Spontaneous Bodily Sensations: The “body high” of methallylescaline can be described as proportionally intense in comparison to its accompanying visual and cognitive effects. It is manifested in a number of forms including an intense soft, warm glow that grows over the body and is capable of becoming extremely physically euphoric. This is most similar to MDMA and MDA and is consistently manifested throughout the experience. This is contrasted by an intensely pleasurable yet sharp, cold electric tingling sensation which moves up and down the body. This is most similar to mescaline and is also consistently manifested throughout the trip. The final physical effect noticed throughout the experience is an intense energetic pins and needles sensation that manifests itself in the form of a continuously shifting and tingling sensation that travels up and down the body in spontaneous waves. This is most similar to 2C-I and is not entirely consistent throughout the trip.

Physical euphoria – Relative to other psychedelics, methallylescaline has been noted for the bodily or physically euphoric aspect that is vaguely reminiscent of other phenethylamines like MDA.

Tactile enhancement: Feelings of enhanced tactile sensations are consistently present at moderate levels throughout most methallylescaline experiences. If Level 8A geometry is reached, an intense sensation of suddenly becoming aware of and being able to feel every single nerve ending across a person’s entire body all at once is consistently present.

Nausea: Nausea is commonly reported when consumed in moderate to high doses and either passes instantly once the user has vomited or gradually fades by itself as the peak sets in.

Muscle cramps: This is uncommon, but is more likely to occur if one is malnourished, dehydrated, or engaged in strenuous activity.

Dosing:

Light: 15-25mg

Common: 25-40mg

Strong: 40-60mg

Onset: 20-60 minutes

Peak: 3-4 hours

Duration: 6-10 hours

https://psychonautwiki.org/wiki/Methallylescaline

https://knowdrugs.app/substances/methallylescaline

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